Regulation of Gene Expression
Often, the regulation of a gene is as important to the life of an organism
as its presence. Numerous strategies for regulation of gene expression
have evolved. These work to control synthesis of a gene's product and
ultimately the phenotype produced by action of the gene product. The lac
operon of E. coli is a paradigm for regulatory schemes and is an
effective model for several basic concepts in the regulation of gene
expression.
The genes for lactose metabolism in E. coli are arranged in an
operon and confer upon E. coli the ability to regulate expression
of genes for lactose metabolism. The lac operon is an
inducible system that exhibits both positive and negative control.
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